Hydrolyzed collagen is a form of collagen and is also called collagen hydrolyzate, gelatin, gelatin hydrolyzate, gelatin hydrolysate, and collagen peptide.
Video Hydrolyzed collagen
Production
Hydrolyzed collagen is produced from collagen found in bone, skin, and animal connective tissue. The hydrolysis process involves breaking the molecular bond between individual collagen strands and peptides using a combination of physical, chemical or biological means. Usually, with skin-derived collagen (Type-I collagens), the skin is hidden in a lime slurry pit for up to 3 months, loosening the collagen bond; the skin is then washed to remove lime, and collagen is extracted in boiling water. The collagen extracted is a concentrated evaporator, dried with a drum dryer, and smoothed.
Maps Hydrolyzed collagen
Characteristics
Hydrolysis resulted in the reduction of collagen fiber protein by about 300,000 Da into smaller peptides. Depending on the hydrolysis process, the peptide will have a wide range of molecular weights associated with physical and chemical denaturation methods.
Amino acid content
The amino acid content of collagen is hydrolyzed equal to collagen. Hydrolyzed collagen contains 19 amino acids, especially glycine, proline and hydroxyproline, which together represent about 50% of the total amino acid content.
Research
Amino acid content
Hydrolyzed collagen contains 8 of 9 essential amino acids, including glycine and arginine - two precursors of amino acids needed for creatine biosynthesis. It contains no tryptophan and lacks isoleucine, threonine, and methionine.
Digestibility
Collagen hydrolyzed collagen bioavailability in mice was demonstrated in a 1999 study; Orally administered 14 C hydrolyzed digested collagen and more than 90% absorbed within 6 hours, with measurable accumulation in cartilage and skin. A 2005 study in humans found hydrolyzed collagen absorbed as a small peptide in the blood.
Skin effect
Ingestion of hydrolyzed collagen may affect the skin by increasing the density of collagen fibrils and fibroblasts, thus stimulating collagen production. It has been suggested, based on rat and in vitro studies, that hydrolyzed collagen peptides have chemotactic properties in fibroblasts or an influence on the growth of fibroblasts.
Joint and bone effects
Several clinical studies reported that the consumption of collagen-hydrolyzed oral collagen lowered joint pain, which with the most severe symptoms showed the greatest benefit. The favorable action is likely due to the accumulation of collagen hydrolyzed in the cartilage and stimulates the production of collagen by chondrocytes, cartilage cells. Several studies have shown that daily hydrolyzed collagen intake increases bone mass density in rats. It appears that the hydrolyzed collagen peptide stimulates the activity of differentiation and osteoblasts - the cells that build up the bones of osteoclasts (bone destroying cells).
However, other clinical trials have produced mixed results. In 2011, the European Food Safety Authority Panel on Diet Products, Nutrition and Allergies concluded that "cause-and-effect relationships have not yet formed between collagen hydrolyzate consumption and joint maintenance". Four other studies reported benefits with no side effects; However, the study was not extensive, and all the recommended studies were further controlled. One study found that oral collagen only improved symptoms in a small percentage of patients and reported nausea as a side effect. Another study reported no increase in disease activity in patients with rheumatoid arthritis. Another study found that collagen treatment can actually lead to exacerbation of rheumatoid arthritis symptoms.
Security issues
Hydrolyzed collagen, such as gelatin, is made from animal by-products from the meat industry, including skin, bone, and connective tissue.
The US Food and Drug Administration (FDA), with support from the Transmissible Spongiform encephalopathy Committee, since 1997 has monitored the potential risks of animal disease transmission, particularly bovine spongiform encephalopathy (BSE). The FDA study concludes: "... measures such as heat, alkaline treatments, and screening can be effective in reducing the level of TSE agent pollution, however, scientific evidence is insufficient at this time to suggest that this treatment will effectively eliminate BSE. if present in the source material. "
Cosmetics
In cosmetics, hydrolyzed collagen can be found in topical creams, acting as a product texture, and moisturizing conditioner.
References
Source of the article : Wikipedia
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